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Clinical Research & Trials

Transparent, rigorous, and patient-centered clinical research advancing next-generation therapeutics, gene therapies, and precision medicine worldwide.

142
Active Trials
8,450+
Patients Enrolled
38
Global Sites
94.2%
Protocol Compliance
AZT-2024-089 Phase III
Recruiting

Efficacy of ZenthOnc-Alpha in Advanced NSCLC

Non-Small Cell Lung Cancer / Oncology

Primary Endpoint Progression-Free Survival
Sites 14 Countries
Target Enrollment 450 Participants
Expected Completion Q3 2026
View Protocol
AZT-2025-112 Phase II
Recruiting

Gene Therapy Vector ZNV-12 for Early-Onset Alzheimer's

Neurodegenerative Disorders / Neurological

Primary Endpoint Cognitive Decline Rate (ADAS-Cog)
Sites 8 Countries
Target Enrollment 180 Participants
Expected Completion Q4 2025
View Protocol
AZT-2023-045 Phase IV
Active, Not Recruiting

Long-Term Cardiovascular Safety of ZenthCore Statin

Hyperlipidemia / Cardiovascular

Primary Endpoint MACE Event Rate
Sites 12 Countries
Target Enrollment 3,200 Participants
Expected Completion Q1 2027
View Protocol
AZT-2025-156 Phase I
Recruiting

First-in-Human: AZR-99 mRNA Therapeutic for SPACA4 Deficiency

Rare Genetic Disorders / Metabolic

Primary Endpoint Safety & Tolerability (SAEs)
Sites 3 Countries
Target Enrollment 42 Participants
Expected Completion Q2 2025
View Protocol
AZT-2022-011 Phase III
Completed

ZenthImmune-Bio in Metastatic Pancreatic Adenocarcinoma

Pancreatic Cancer / Oncology

Primary Endpoint Overall Survival
Sites 9 Countries
Target Enrollment 310 Participants
Completion Date Q4 2024
View Results
AZT-2025-103 Phase II
Active, Not Recruiting\n

Nanoparticle Delivery System for Refractory Atrial Fibrillation

Cardiac Arrhythmia / Cardiovascular

Primary Endpoint Afib Burden Reduction
Sites 6 Countries
Target Enrollment 120 Participants
Expected Completion Q1 2026
View Protocol

Research Standards & Ethics

All Aevum Zenth clinical trials are conducted in strict adherence to international regulatory frameworks, prioritizing patient safety, data integrity, and transparent reporting.

🛡️

IRB & Ethics Approval

Every protocol undergoes rigorous independent ethical review before initiation, ensuring informed consent and patient rights.

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FDA & EMA Aligned

Trials follow 21 CFR Part 11, ICH-GCP guidelines, and EU Clinical Trials Regulation No 536/2014 standards.

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HIPAA & GDPR Compliant

Participant data is encrypted, anonymized, and stored in certified secure infrastructure with zero third-party leakage.

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Open Data Commitment

Positive and negative results are published transparently. Datasets are shared with qualified researchers upon request.

For Patients & Caregivers

Explore eligible studies, understand enrollment criteria, or speak with our patient advocacy team for confidential guidance.

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For Research Partners & Sites

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