v3.8.2 | Active Inference Pipeline

Structured Intelligence for
Unstructured Clinical Data

Aevum Zenth Clinical NLP Ontologies transform free-text EHR notes, trial documents, and medical literature into queryable, standardized knowledge graphs with sub-50ms latency.

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Ontology Architecture

Our ontology engine maps clinical terminology across 7 major standards into a unified vector-semantic space. Context-aware resolution handles negation, uncertainty, temporal progression, and patient-specific modifiers with clinically validated precision.

Terminology Fusion

Real-time alignment of SNOMED-CT, LOINC, RxNorm, ICD-10/11, UMLS, and MedDRA into a single queryable graph.

Cross-Mapping

Context Resolution

Entity linking with negation detection, hypothetical framing, and historical vs. current status classification.

Clinical NER

Temporal Graphing

Longitudinal event tracking with onset, resolution, recurrence, and medication-adherence modeling.

Time-Aware

Performance Specifications

Metric Value Benchmark / Notes
Concept Coverage (UMLS) 94.7% vs. 2024 CRAFT benchmark
Inference Latency (10k tokens) < 42ms GPU-accelerated, v3.8.2
F1 Score (Entity Extraction) 0.931 Multi-disease cohort validation
Throughput 12,000 docs/hr Single node, optimized batching
Supported Formats FHIR R4, HL7 v2, JSON-LD, DICOM Native adapters included
Update Cadence Monthly + Real-time delta Aligns with IHE & HL7 releases
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Integration & API

Access the ontology engine via REST, gRPC, or native SDKs. All endpoints return structured JSON with confidence scoring, source offsets, and mapped concept IDs.

POST /v3/ontology/extract
Content-Type: application/json

{ "text": "Patient denies chest pain, no history of MI. Started lisinopril 10mg daily.", "standards": ["SNOMED-CT", "RxNorm"], "context": "encounter" }

SDK Support

  • Python (PyPI: aevum-clinical-nlp)
  • R (CRAN & Bioconductor)
  • Java / Kotlin (Maven Central)
  • FHIR R4 Bundle Generator
  • GraphQL Schema for Knowledge Graph
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Compliance & Security

Built for regulated healthcare environments. All inference pipelines are deployed within isolated VPCs with zero data retention by default. Audit trails, PII redaction, and role-based access are enforced at the gateway level.

HIPAA Compliant
GDPR Ready
SOC 2 Type II
ISO 27001
21 CFR Part 11
FDA SaMD Pathway Aligned
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Primary Use Cases

Real-World Evidence (RWE)

Extract patient cohorts, adverse events, and treatment pathways from unstructured EHR notes for observational studies.

Prior Authorization Automation

Auto-map clinical indications to payer criteria using standardized ontology codes and evidence strength scoring.

Clinical Trial Enrichment

Identify eligible candidates across enterprise health networks by resolving eligibility criteria against longitudinal records.

Medical Literature Mining

Ingest PubMed, clinical registries, and trial reports to build up-to-date knowledge graphs for CDS systems.

Deploy Clinical NLP Ontologies

Request sandbox access, download the technical whitepaper, or schedule an architecture review with our Health Sciences AI team.

Request API Credentials → Download Whitepaper (PDF) Contact AI Team