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142
Active Trials
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38
Phase III Programs
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64
Partner Sites
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1,200+
Publications

Clinical Trial Pipeline

Real-time status of our therapeutic candidates across multiple neurological and psychiatric indications.

AZN-742-03 Recruiting

Dual Kinase Inhibitor for Early-Stage Alzheimer's

Indication: Mild Cognitive Impairment & Early Alzheimer's Disease

NCT05829103 Multi-center 12-month primary endpoint
AZN-918-01 Active

Rapid-Acting Glutamatergic Modulator for MDD

Indication: Treatment-Resistant Major Depressive Disorder

NCT06102847 Double-blind 6-week endpoint
AZN-BC-22 Recruiting

Non-Invasive BCI for Locked-In Syndrome Rehabilitation

Indication: Severe Motor Neuron Disease & Brainstem Stroke

IDE Approved EEG-fNIRS Hybrid 18-month follow-up
AZN-604-02 Completed

Lysosomal Clearance Enhancer for Parkinson's

Indication: Early Parkinson's Disease (Huntingtin Q75+/− models)

NCT05441920 Primary endpoint met Data readout Q2 2025

Neurotech & AI-Driven Diagnostics

Our clinical neuroscience pipeline is accelerated by proprietary neuroimaging AI, multi-omics biomarker panels, and closed-loop neurostimulation platforms. We integrate real-world data with longitudinal trial endpoints to identify responders earlier and reduce development timelines.

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AI-Powered Neuroimaging & Biomarker Discovery
Adaptive Trial Design & Digital Endpoints
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Precision Stratification via Multi-Omics Profiling

Global Clinical Network

Strategic partnerships with leading academic medical centers, specialty clinics, and independent research institutions.

Zenth Neuro Institute
Neo Geneva, Global HQ
Phase I/II UnitBCI Lab
Massachusetts General Hospital
Boston, USA
PsychiatryImaging Core
UCL Queen Square Institute
London, UK
NeurodegenerationBiomarkers
Tokyo Metropolitan Neurology Center
Tokyo, Japan
Motor DisordersClinical Ops
Karolinska University Hospital
Stockholm, Sweden
NeuroimmunologyPhase III
AIIMS Clinical Trials Unit
New Delhi, India
High-Volume EnrollmentPsychiatry

Recent Publications & Data Readouts

Peer-reviewed findings, conference presentations, and regulatory milestones from our neuroscience teams.

Nature Neuroscience | 2025

Multi-modal AI prediction of treatment response in late-stage Alzheimer's clinical trials

Zenth Neuro Group, et al.

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The Lancet Psychiatry | 2025

Phase II results of AZN-918: Rapid symptom reduction in TRD without dissociative side effects

Clinical Psych Division, Aevum Zenth

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Neuron | 2024

Closed-loop DBS optimization using real-time biomarker feedback in Parkinson's disease

Neurotech & Engineering Labs

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Partner With Our Neuroscience Division

Whether you're a clinical site, academic researcher, or biotech innovator, we're expanding our trial network and technology partnerships globally.